When an image-conscious wild child takes a strange new drug at a party, she undergoes a shocking transformation. Desperate to reverse the effects of the drug, she is horrified to discover that she has become the key to saving the human race.

Theo Abrams is an ex-Cape Town fireman suffering from severe Post-Traumatic Stress Disorder. Unable to return to work due to the psychological trauma sustained during a failed rescue mission, an increasingly frustrated and volatile Theo's world is rocked when one morning, he wakes up next to his wife's murdered corpse with no recollection of what transpired and all evidence suggesting that he's killed her. When the police label him as the prime suspect, Theo goes on the run, and is soon being hunted by Deputy Chief of Police, Alan Shard, a notoriously ruthless soldier of the law, who is hell-bent on catching Theo as one last act of service before he officially retires. However, when an unknown third party is thrown into the mix, Theo discovers an alarming connection between the sinister forces hunting him in an attempt to silence him permanently for a reason he can't comprehend; and a recent investigation his wife was conducting into a global armament contractor. When connecting the dots becomes a matter of life and death, Theo becomes embroiled in a desperate fight for survival and must figure out who really murdered his wife before a terrifying conspiracy changes the course of a nation forever.

狡猾的骗子泰迪·穆雷托（弗兰克·格里罗饰）驾驶着满是子弹的皇冠维克在内华达沙漠中呼啸驰骋。为了躲避杀手鲍勃·维迪克（杰拉德·巴特勒饰），他制定了一个计划：袭击初出茅庐的警察瓦莱丽·杨（亚历克西斯·劳德饰) ，令其将自己逮捕并关押在小镇警察局。但显然，监狱不能长久保护穆雷托。维迪克同样通过计谋进入拘留所，寻找完成刺杀任务。　　但此时，一个刺客（托比·哈斯饰）的到来，引发了警察局的全面的混乱...